A new heterozygous frameshift variant in keratin 10 resulting in ichthyosis hystrix in a father and daughter

• Lauren Kerry Knight, MBChB (UCT), MSc (Med), FCDERM, MMed (Derm),
• John McGrath, MD, FRCP, FmedSci,
• Linda Ozoemena, BSc Hons, PhD,
• Riyaadh Roberts, MBChB, MMed (UCT), FCPath(SA) Anat,
• Carol Hlela, MBChB, FCDerm, MMed (Derm), MSc GHS, DPhil (Oxon)

Affiliations

Lauren Kerry Knight, MBChB (UCT), MSc (Med), FCDERM, MMed (Derm)

Division of Dermatology, Red Cross Children’s Hospital, University of Cape Town, Cape Town, South Africa; Correspondence to: Lauren Kerry Knight, MBChB (UCT), MSc (Med), FCDERM, MMed (Derm), Division of Dermatology, Groote Schuur Hospital, Ward G23, Anzio Road Observatory, Cape Town, 7925, South Africa.

John McGrath, MD, FRCP, FmedSci

St John’s Institute of Dermatology and National Diagnostic Epidermolysis Bullosa Laboratory, London, United Kingdom

Linda Ozoemena, BSc Hons, PhD

St John’s Institute of Dermatology and National Diagnostic Epidermolysis Bullosa Laboratory, London, United Kingdom

Riyaadh Roberts, MBChB, MMed (UCT), FCPath(SA) Anat

Division of Anatomical Pathology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa; National Health Laboratory Services, Johannesburg, South Africa

Carol Hlela, MBChB, FCDerm, MMed (Derm), MSc GHS, DPhil (Oxon)

Division of Dermatology, Red Cross Children’s Hospital, University of Cape Town, Cape Town, South Africa