Invasive fungal infection by Aspergillus flavus in immunocompetent hosts: A case series and literature review

Abstract

Invasive aspergillosis usually affects immunocompromised hosts with variable manifestations depending on the site of infection. In this article, we present two cases of invasive Aspergillosis in two non-immunocompromised patients; both cases had a paranasal sinuses infection, with intraorbital and intracranial extension, requiring surgery and antifungal treatment with Voriconazole. These cases were initially diagnosed as paranasal sinus neoplasms. However, the pathology and microbiology studies revealed invasive fungal infection by Aspergillus flavus Keywords: Aspergillosis, Invasive Aspergillosis, Immunocompetent host, Paranasal sinus