Data in Brief (Feb 2018)
Data of expression status of miR- 29a and its putative target mitochondrial apoptosis regulatory gene DRP1 upon miR-15a and miR-214 inhibition
- Muhammad Ishtiaq Jan,
- Riaz Anwar Khan,
- Abdul Malik,
- Tahir Ali,
- Muhammad Bilal,
- Long Bo,
- Abdul Sajid,
- Naseeb Urehman,
- Nayyar Waseem,
- Javed Nawab,
- Murad Ali,
- Abdul Majeed,
- Hamid Ahmad,
- Sohail Aslam,
- Sadia Hamera,
- Aneesa Sultan,
- Mariam Anees,
- Qamar Javed,
- Iram Murtaza
Affiliations
- Muhammad Ishtiaq Jan
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan
- Riaz Anwar Khan
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Abdul Malik
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Tahir Ali
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan
- Muhammad Bilal
- Livestock and Dairy Development, Veterinary Research Institute, Peshawar, Pakistan
- Long Bo
- Peking Union medical College, Beijing, China
- Abdul Sajid
- Livestock and Dairy Development, Veterinary Research Institute, Peshawar, Pakistan
- Naseeb Urehman
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Nayyar Waseem
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Javed Nawab
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Murad Ali
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Abdul Majeed
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Hamid Ahmad
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Sohail Aslam
- Department of Cardiovascular Surgery, Lady Reading Hospital Peshawar, Pakistan
- Sadia Hamera
- LUMS, Department of Biology, SBASSE, Lahore, Pakistan
- Aneesa Sultan
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan
- Mariam Anees
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan
- Qamar Javed
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan; PINST Department, Preston University, Islamabad, Pakistan
- Iram Murtaza
- Signal Transduction Lab, Department of Bio-Chemistry, Faculty of Biological Sciences, Quaid-i-Azam University Islamabad, Islamabad, Pakistan; Corresponding author.
- Journal volume & issue
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Vol. 16
pp. 1000 – 1004
Abstract
Data is about the mitochondrial apoptosis regulatory framework genes PUMA, DRP1 (apoptotic), and ARC (anti-apoptotic) analysis after the employment of their controlling miRNAs inhibitors. The data represents putative conserved targeting of seed regions of miR-15a, miR-29a, and miR-214 with respective target genes PUMA, DRP1, and ARC. Data is of cross interference in expression levels of one miRNA family, miR-29a and its putative target DRP1 upon the inhibitory treatment of other miRNAs 15a and 214. Keywords: DRP1, miR-15a, Apoptosis, miRNAs inhibition
