Synthesis and In Silico Evaluation of Potential Insecticide Activity of Benzamides

Abstract

In order to find alternative pesticides, a series of benzamide derivatives was synthesized. An in silico inverted virtual screening protocol considering the 13 common insecticide protein targets was used to evaluate the potential insecticide activity of these molecules and identify the most likely targets. The results suggest important clues for the development of this class of derivatives as alternative insecticides.

Keywords

• benzamides
• insecticides
• <i>Spodoptera frugiperda</i>
• pesticides
• computational studies