Antibiotics (Apr 2022)

Granulomatous Cheilitis or Tuberculid?

  • Georgi Tomov,
  • Parvan Voynov,
  • Svitlana Bachurska

DOI
https://doi.org/10.3390/antibiotics11040522
Journal volume & issue
Vol. 11, no. 4
p. 522

Abstract

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The granulomatous cheilitis (GC) presents a heterogeneous group of disorders characterised by a granulomatous inflammation/reaction of the lips to various stimuli. Numerous etiologies have been proposed, including genetic, immunologic, allergic and infectious. Among the secondary causes of GC, an infection by Mycobacterium tuberculosis (MBT) should be considered. In such cases, the GC could be the clinical presentation of a tuberculid resulting from a hypersensitivity reaction to an underlying focus of active (ATBI) or latent tuberculosis infection (LTBI). This communication describes an immunocompetent patient diagnosed with GC resulting from tuberculid, who responded well to Isoniazid monotherapy.

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