REGENERATION OF THE CIRRHOTIC LIVER RABBITS IN INTRAHEPATIC INTRODUCTION KRIOPRECIPITATA

Abstract

Purpose: to study the effect of cryoprecipitate, keeping percutaneously under ultrasound on cirrhotic liver tissue 22 rabbits. Materials and methods: cirrhosis of the liver in rabbits was caused by subcutaneous injection of carbon tetrachloride for three months.Results: after receiving 22 the rabbit liver cirrhosis were divided into two groups. To stimulate liver regeneration first group (12 rabbits) was injected into the liver cryoprecipitate second (10 rabbits) -gepatoprotektor. Cryoprecipitate was injected percutaneously into the liver, puncture method under ultrasound, hepatoprotector - subcutaneously. The results were evaluated by performing a liver biopsy under ultrasound guidance. Morphologically proved that under the influence of cryoprecipitate accelerates regeneration of liver tissue, reduced macrophage infiltration LIFO-formed hepatic lobule with the correct beamed structure of hepatocytes. Regeneration processes in the liver accompanied by improvement of the clinical picture of the disease. After the introduction of hepatoprotector reliable morphological and clinical changes were made.Summary: thus, cryoprecipitate entered puncture method in cirrhotic liver tissue regeneration is a stimulant that improves the clinical and morphological picture of the disease. Keywords: liver, cirrhosis, regeneration, cryoprecipitate, rabbits, ultrasound.

Keywords

• liver, cirrhosis, regeneration, cryoprecipitate, rabbits, ultrasound