Impact of COVID-19 infection on clinical outcomes of adult burn patients: A retrospective observational cohort study in Iran
Mahmood Omranifard,
Mahdi Rasti,
Mohammad Ali Hoghoughi,
Danyal Omranifard,
Fahimeh Beigi,
Majid Kalbasi Gharavi,
Amir Parniaei,
Morteza Mirzaei,
Maryam Mahabadi,
Nazila Farnoush,
Amirreza Fotoohi
Affiliations
Mahmood Omranifard
MD, Professor Doctor, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Mahdi Rasti
MD, Professor Doctor, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Mohammad Ali Hoghoughi
MD, Associate Professor, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Danyal Omranifard
Medical student, Medical School, Kashan University of Medical Sciences, Kashan, Esfahan, Iran
Fahimeh Beigi
PhD, Lab Expert, Pharmaceutics Department, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Majid Kalbasi Gharavi
MD, Fellowship student, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Amir Parniaei
MD, Fellowship student, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Morteza Mirzaei
MD, Fellowship student, Department of Plastic and Reconstructive Surgery, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
Maryam Mahabadi
MD, MSc, Clinical Trial Specialist, Ethica Data Ltd, Toronto, Ontario, Canada; Corresponding author at: Ethica Data Services Inc., 4109 - 295 Adelaide St W, Toronto, ON M5V 0L4, Canada.
Nazila Farnoush
MD, Associate Professor, Department of Plastic and Reconstructive Surgery, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Amirreza Fotoohi
Medical student, Medical School, Isfahan University of Medical Sciences, Isfahan, Esfahan, Iran
The COVID-19 pandemic has exacerbated the significance of burn injuries as a critical public health challenge, demanding the exploration of effective strategies for prevention and care, particularly for individuals with burns. This retrospective observational cohort study aimed to analyze the characteristics of adult burn patients admitted to three reference centers in Iran from October 2020 to October 2023. The study focused on patients and burn wound characteristics, complications and morbidities, and treatment plans. Among the 382 patients aged 20 to 84, our findings suggested that being male decreased the likelihood of COVID-19 infection by about 77 %. Thermal burns accounted for 50.2 % of COVID-19-positive patients and 49.8 % of COVID-19-negative patients. Notably, the risk of COVID-19 infection increased with higher degrees of burn (p = 0.006) in both groups. Among the complications, pneumonia (p = 0.003) and paralytic ileus (p = 0.015) were significantly more common in COVID-19-positive patients. Additionally, COVID-19-positive patients underwent more frequent interventions such as skin grafting (p = 0.035) and surgical debridement (p = 0.030). These findings emphasize the importance of a carefully planned and proactive multidisciplinary management strategy to ensure optimal care for burn patients.
