Urology Case Reports (Jul 2022)

Infant prostatic Rhabdomyosarcoma: A diagnostic and therapeutic challenge

  • Sohail Dhanji,
  • Leonardo D. Borregales,
  • Nicolette K. Janzen,
  • Guilherme Godoy,
  • Maren Y. Fuller,
  • Jason K. Au

Journal volume & issue
Vol. 43
p. 102116

Abstract

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The following case report describes a case of prostatic rhabdomyosarcoma in a 6-month-old male who presented with urinary retention and constipation. MRI showed a prostatic mass that was displacing the rectum and bladder, leading to bladder outlet obstruction. A suprapubic tube was placed for urinary diversion and a transvesical approach was used for tissue diagnosis. Biopsy confirmed the diagnosis of prostatic rhabdomyosarcoma. Patient underwent chemotherapy regiment with VAC (vincristine, actinomycin D and cyclophosphamide) and subsequently ifosfamide and doxorubicin. Eventually, due to tumor progression, the patient underwent a radical cystoprostatectomy with pelvic lymph node dissection and ileal conduit.

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