Journal of Orthopaedic Reports (Mar 2025)

Beyond the surface: Orthopaedic blister management “A review of the literature”

  • Amanda O'Halloran,
  • Rao Mazz Bin Shakir,
  • Yahyia Faisal Ibrahim Mohamed Alamin,
  • Anant Mahapatra

Journal volume & issue
Vol. 4, no. 1
p. 100386

Abstract

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Fracture blisters, often termed “trauma blisters” or “epidermolysis,” are vesicles filled with clear fluid or blood that form on the skin within 24–48 h following an acute fracture.1 Their precise aetiology remains unclear, though it is hypothesised that dermal-epidermal junction damage due to severe shear stress plays a critical role.Blisters often appear near fractures, particularly in the lower extremities. They can emerge as soon as 6 h to three weeks post-injury or surgery, delaying definitive fracture management due to the risk of wound complications.Management involves documenting blister characteristics and deciding between conservative and surgical approaches based on blister condition and patient factors.The aim for this review is to give a brief overview of the available literature in an attempt to consolidate current treatment recommendations.

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