Communications Biology (May 2021)

Lineage-level divergence of copepod glycerol transporters and the emergence of isoform-specific trafficking regulation

  • Marc Catalán-García,
  • François Chauvigné,
  • Jon Anders Stavang,
  • Frank Nilsen,
  • Joan Cerdà,
  • Roderick Nigel Finn

DOI
https://doi.org/10.1038/s42003-021-01921-9
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 14

Abstract

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Marc Catalán-Garcia et al. examine evolutionary divergence of aquaglyceroporins (GLPs) in copepods, observing that these genes are subject to high rates of gene duplication across species. They also report tissue- and sex-specific expression of GLP splice variants in the parasitic copepod, L. salmonis, that in turn exhibit PKA- or PKC-dependent changes in membrane trafficking. Altogether, these results suggest that mutations in GLP genes with precise regulation of intracellular tracking may be related to neofunctionalization in these species.