Flexible electronics for cardiovascular monitoring on complex physiological skins
Tianqi Zhang,
Yunshen Wang,
Xingdong Feng,
Yizhou Zuo,
Hannong Yu,
Hong Bao,
Fan Jiang,
Shan Jiang
Affiliations
Tianqi Zhang
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China
Yunshen Wang
Department of Pneumology, Tianjin Children’s Hospital, Children’s Hospital, Tianjin University, Tianjin 300204, China
Xingdong Feng
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China
Yizhou Zuo
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China
Hannong Yu
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China
Hong Bao
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China; State Key Laboratory of Electromechanical Integrated Manufacturing of High-performance Electronic Equipments, Xidian University, Xi’an 710071, China
Fan Jiang
Geriatric Medical Center, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou 570311, China; Corresponding author
Shan Jiang
Hangzhou Institute of Technology, Xidian University, Hangzhou 311200, China; State Key Laboratory of Electromechanical Integrated Manufacturing of High-performance Electronic Equipments, Xidian University, Xi’an 710071, China; Corresponding author
Summary: Cardiovascular diseases (CVDs) pose a significant global health threat, responsible for a considerable portion of worldwide mortality. Flexible electronics enable continuous, noninvasive, real-time, and portable monitoring, providing an ideal platform for personalized healthcare. Nevertheless, challenges persist in sustaining stable adherence across diverse and intricate skin environments, hindering further advancement toward clinical applications. Strategies such as structural design and chemical modification can significantly enhance the environmental adaptability and monitoring performance of flexible electronics. This review delineates processing techniques, including structural design and chemical modification, to mitigate signal interference from sebaceous skin, motion artifacts from the skin in motion, and infection risks from fragile skin, thereby enabling the accurate monitoring of key cardiovascular indicators in complex physiological environments. Moreover, it delves into the potential for the strategic development and improvement of flexible electronics to ensure their alignment with complex physiological environment requirements, facilitating their transition to clinical applications.