Nature Communications (May 2017)

Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension

  • Léa Marie,
  • Chiara Rapisarda,
  • Violette Morales,
  • Mathieu Bergé,
  • Thomas Perry,
  • Anne-Lise Soulet,
  • Clémence Gruget,
  • Han Remaut,
  • Rémi Fronzes,
  • Patrice Polard

DOI
https://doi.org/10.1038/ncomms15638
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 14

Abstract

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Bacterial homologous recombination involves the actions of RadA and RecA to promote single-stranded DNA integration. Here the authors report the structure of RadA fromStreptococcus pneumoniaeand demonstrate that it acts as a hexameric DnaB-type helicase.