Nature Communications (Feb 2022)

Single-cell gene fusion detection by scFusion

  • Zijie Jin,
  • Wenjian Huang,
  • Ning Shen,
  • Juan Li,
  • Xiaochen Wang,
  • Jiqiao Dong,
  • Peter J. Park,
  • Ruibin Xi

DOI
https://doi.org/10.1038/s41467-022-28661-6
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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Gene fusions are an important class of mutations in tumor genomes. Here, the authors develop a single-cell gene fusion detection method scFusion and demonstrate its applications in cancer single-cell studies.