Detailed analysis of distorted retinal and its interaction with surrounding residues in the K intermediate of bacteriorhodopsin

Shoun Taguchi; Satomi Niwa; Hoang-Anh Dao; Yoshihiro Tanaka; Ryota Takeda; Shuya Fukai; Kazuya Hasegawa; Kazuki Takeda

doi:10.1038/s42003-023-04554-2

Communications Biology (Feb 2023)

Detailed analysis of distorted retinal and its interaction with surrounding residues in the K intermediate of bacteriorhodopsin

Shoun Taguchi,
Satomi Niwa,
Hoang-Anh Dao,
Yoshihiro Tanaka,
Ryota Takeda,
Shuya Fukai,
Kazuya Hasegawa,
Kazuki Takeda

Affiliations

Shoun Taguchi: Department of Chemistry, Graduate School of Science, Kyoto University
Satomi Niwa: Department of Chemistry, Graduate School of Science, Kyoto University
Hoang-Anh Dao: Department of Chemistry, Graduate School of Science, Kyoto University
Yoshihiro Tanaka: Department of Chemistry, Graduate School of Science, Kyoto University
Ryota Takeda: Department of Chemistry, Graduate School of Science, Kyoto University
Shuya Fukai: Department of Chemistry, Graduate School of Science, Kyoto University
Kazuya Hasegawa: Structural Biology Division, Japan Synchrotron Radiation Research Institute (JASRI)
Kazuki Takeda: Department of Chemistry, Graduate School of Science, Kyoto University

DOI: https://doi.org/10.1038/s42003-023-04554-2
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 9

Abstract

Read online

Crystal structures and quantum mechanical calculations reveal the interaction and photoisomerized conformation of the retinal chromophore in the K intermediate of bacteriorhodopsin (bR), giving insights into light-driven bR proton pumping.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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