Iranian Journal of Public Health (Jun 2007)

Th1/Th2 Cytokines in Psoriasis

  • Z Jadali,
  • M Izad,
  • MB Eslami,
  • P Mansouri,
  • R Safari,
  • P Bayatian,
  • A Mirshafiey,
  • AR Salehi Nodeh

Journal volume & issue
Vol. 36, no. 2

Abstract

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Background: The aim of this study was to determine the Th1 and Th2 serum cytokines, in patients with psoriasis and to com¬pare their cytokine levels with those of normal control subjects. Methods: Serum levels of Interferon-gamma (IFN-γ), Interleukin-2 (IL-2), Interleukin-4 (IL-4), and Interleukin-10 (IL-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in 40 normal controls. Results: Compared with control subjects, patients with psoriasis had elevated levels of IFN-γ and IL-2 (P