Clinical Ophthalmology (Jun 2015)
Microbiologic spectrum and susceptibility of isolates in delayed post-cataract surgery endophthalmitis
Abstract
Animesh Jindal,1 Avinash Pathengay,1 Subhadra Jalali,2 Annie Mathai,2 Rajeev Reddy Pappuru,2 Raja Narayanan,2 Jay Chhablani,2 Savitri Sharma,3,4 Taraprasad Das,2,3 Harry W Flynn Jr51L V Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, India; 2Srimati Kannuri Santhamma Centre for Vitreoretinal Diseases, L V Prasad Eye Institute, KAR Campus, Hyderabad, India; 3L V Prasad Eye Institute, Bhubaneswar Eye Institute, Bhubaneswar, Odisha, India; 4Jhaveri Microbiology Centre, L V Prasad Eye Institute, KAR Campus, Hyderabad, India; 5Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USAAbstract: The objective of this study was to evaluate the microbiological spectrum and antimicrobial susceptibility of isolates in delayed post-cataract surgery endophthalmitis. A retrospective review of 33 consecutive patients with culture proven delayed post-cataract surgery endophthalmitis was done from January 2006 to March 2013. There were 22 bacterial and eleven fungal cases. Common isolates were Streptococci (seven cases), coagulase-negative staphylococci (five), Gram-negative bacilli (seven), Nocardia (two), Aspergillus (five), Candida (five). Gram-positive cocci were most susceptible to vancomycin and gatifloxacin (91.7%). Gram-negative isolates were most susceptible to ofloxacin (85.7%). Fungi being slow growing organisms are an important cause of delayed post-cataract surgery endophthalmitis.Keywords: delayed endophthalmitis, microbiology, antibiotic sensitivity