Biomedical applications of magnetosomes: State of the art and perspectives

Gang Ren; Xia Zhou; Ruimin Long; Maobin Xie; Ranjith Kumar Kankala; Shibin Wang; Yu Shrike Zhang; Yuangang Liu

Bioactive Materials (Oct 2023)

Biomedical applications of magnetosomes: State of the art and perspectives

Gang Ren,
Xia Zhou,
Ruimin Long,
Maobin Xie,
Ranjith Kumar Kankala,
Shibin Wang,
Yu Shrike Zhang,
Yuangang Liu

Affiliations

Gang Ren: Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; College of Materials Science and Engineering, Huaqiao University, Xiamen, Fujian, 361021, China
Xia Zhou: Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; College of Chemical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China
Ruimin Long: College of Chemical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China
Maobin Xie: Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 511436, China
Ranjith Kumar Kankala: College of Chemical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; Fujian Provincial Key Laboratory of Biochemical Technology, Xiamen, Fujian, 361021, China
Shibin Wang: Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; College of Materials Science and Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; Fujian Provincial Key Laboratory of Biochemical Technology, Xiamen, Fujian, 361021, China
Yu Shrike Zhang: Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA; Corresponding author.
Yuangang Liu: Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; College of Chemical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China; Fujian Provincial Key Laboratory of Biochemical Technology, Xiamen, Fujian, 361021, China; Corresponding author. Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian, 361021, China.

Journal volume & issue: Vol. 28
pp. 27 – 49

Abstract

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Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent bioavailability, and easily modifiable functional groups. In this review, we first discuss the mechanisms of magnetosome formation and describe various modification methods. Subsequently, we focus on presenting the biomedical advancements of bacterial magnetosomes in biomedical imaging, drug delivery, anticancer therapy, biosensor. Finally, we discuss future applications and challenges. This review summarizes the application of magnetosomes in the biomedical field, highlighting the latest advancements and exploring the future development of magnetosomes.

Published in Bioactive Materials

ISSN: 2452-199X (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials; Science: Biology (General)
Website: https://www.keaipublishing.com/en/journals/bioactive-materials/

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