Respiratory Medicine Case Reports (Jan 2022)

Unusual presentation of a small cell lung cancer with bilateral breast metastases: Case report and a brief review of the literature

  • Mark Bannon,
  • Creticus Marak,
  • Adrita Ashraf,
  • Chelsea Smith,
  • Matthew Nunley,
  • Achuta Kumar Guddati,
  • Prashant Kaushik

Journal volume & issue
Vol. 38
p. 101693

Abstract

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Small cell lung cancer (SCLC) is a smoker's disease and occurs almost exclusively in smokers. SCLC is a high-grade neuroendocrine tumor and commonly presents as a central tumor with bulky mediastinal adenopathy. It is notorious for causing widespread disease and paraneoplastic syndromes. The usual sites of metastasis include the liver, brain, bone, and adrenals. SCLC presenting with breast metastasis is unusual; however, there are reports of unilateral and bilateral breast metastases. SCLC with bilateral breast metastases is extremely rare, with only five previously reported cases available in the literature. We are taking this opportunity to report and add to the growing literature on the unusual presentation of a small cell lung cancer with bilateral breast metastases.