BMC Biology (Sep 2011)

Mobile DNA transposition in somatic cells

  • Kazazian Haig H

DOI
https://doi.org/10.1186/1741-7007-9-62
Journal volume & issue
Vol. 9, no. 1
p. 62

Abstract

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Abstract It had been long assumed that almost all insertions of mobile DNA elements occurred during germ-cell development rather than in somatic-cell development, but solid evidence for transposition in somatic cells is now accumulating. To add to this evidence, a recent paper in Mobile DNA reports the somatic transposition of a site-specific retrotransposon, R2, into its insertion site in 28S ribosomal DNA in Drosophila embryos. See research article: http://www.mobilednajournal.com/content/2/1/11