Efficacy of Low‐dose (2 millicurie) versus Standard‐dose (4 millicurie) Radioiodine Treatment for Cats with Mild‐to‐Moderate Hyperthyroidism

Abstract

Background Radioiodine (131I) is effective treatment for hyperthyroidism in cats, but optimal dose to restore euthyroidism without inducing hypothyroidism is unclear. Treatment‐induced hypothyroidism can lead to azotemia and reduced duration of survival. Objective To compare efficacy and short‐term outcomes of low‐dose 131I versus higher, standard‐dose 131I as treatment for hyperthyroidism. Animals A total of 189 client‐owned cats undergoing 131I treatment for mild‐to‐moderate hyperthyroidism (serum T4 ≥ 4.0 μg/dL and 95% with reduced frequency of iatrogenic hypothyroidism and azotemia.

Keywords

• 131I
• Feline
• Radioactive iodine
• Radiotherapy
• Thyroid gland