Nature Communications (May 2017)

Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions

  • Manuel Hessenberger,
  • Ralf M. Zerbes,
  • Heike Rampelt,
  • Séverine Kunz,
  • Audrey H. Xavier,
  • Bettina Purfürst,
  • Hauke Lilie,
  • Nikolaus Pfanner,
  • Martin van der Laan,
  • Oliver Daumke

DOI
https://doi.org/10.1038/ncomms15258
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 11

Abstract

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The MICOS complex has an essential role in crista junction formation and mitochondrial inner membrane morphology. Here, the authors show that one of its components, Mic60, known to form contact sites between inner and outer membranes, also displays membrane-shaping activity.