PLoS ONE (Jan 2024)

Clinical and radiologic features of soft tissue sarcoma in trunk and extremities that underwent unplanned excision.

  • Yujin Seo,
  • Young Cheol Yoon,
  • Hyun Su Kim,
  • Sung Wook Seo,
  • Yoon-La Choi,
  • Kyunga Kim,
  • Ji Hyun Lee

DOI
https://doi.org/10.1371/journal.pone.0311300
Journal volume & issue
Vol. 19, no. 12
p. e0311300

Abstract

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BackgroundTo identify the clinical and imaging characteristics of soft tissue sarcomas (STS) of the trunk and extremities that undergo unplanned excision.MethodsThis retrospective study evaluated the data of patients with STS in the trunk or extremities between January 2008 and December 2021. Patients were divided into unplanned and planned excision groups based on their initial treatment. The distribution of histologic subtypes was analyzed, and the magnetic resonance imaging features were evaluated. Multivariable logistic regression was performed to identify variables independently associated with unplanned excision.ResultsA total of 305 patients (mean age±standard deviation, 51±16.4 years; 179 males) were analyzed. The most prevalent subtype in the unplanned excision group was myxofibrosarcoma (22.3%). The unplanned excision group had a significantly smaller tumor size (p ConclusionMyxofibrosarcoma is associated with a high frequency of unplanned excision. A significant number of patients in the unplanned excision group demonstrated a lobulated shape and peritumoral abnormalities. Only small tumor size and superficial location were independently associated with unplanned STS excision.