Synthesis and Application of Salicylhydrazone Probes with High Selectivity for Rapid Detection of Cu<sup>2+</sup>
Tianzhu Shi,
Zhengfeng Xie,
Xinliang Mo,
Yulong Feng,
Tao Peng,
Fuyong Wu,
Mei Yu,
Jingjing Zhao,
Li Zhang,
Ju Guo
Affiliations
Tianzhu Shi
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Zhengfeng Xie
Oil & Gas Field Applied Chemistry Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China
Xinliang Mo
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Yulong Feng
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Tao Peng
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Fuyong Wu
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Mei Yu
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Jingjing Zhao
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Li Zhang
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Ju Guo
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China
Using the aldehyde amine condensation procedure and the triphenylamine group as the skeleton structure, the new triphenylamine-aromatic aldehyde-succinylhydrazone probe molecule DHBYMH was created. A newly created acylhydrazone probe was structurally characterized by mass spectrometry (MS), NMR, and infrared spectroscopy (FTIR). Fluorescence and UV spectroscopy were used to examine DHBYMH’s sensing capabilities for metal ions. Notably, DHBYMH achieved a detection limit of 1.62 × 10−7 M by demonstrating exceptional selectivity and sensitivity towards Cu2+ ions in an optimum sample solvent system (DMSO/H2O, (v/v = 7/3); pH = 7.0; cysteine (Cys) concentration: 1 × 10−4 M). NMR titration, high-resolution mass spectrometry analysis, and DFT computation were used to clarify the response mechanism. Ultimately, predicated on DHBYMH’s reversible identification of Cu2+ ions in the presence of EDTA, a molecular logic gate was successfully designed.
