Clinical Interventions in Aging (Mar 2024)

Risk Factors for 30-Days Mortality After Proximal Femoral Fracture Surgery, a Cohort Study

  • de Haan E,
  • Roukema GR,
  • van Rijckevorsel VA,
  • Kuijper TM,
  • de Jong L

Journal volume & issue
Vol. Volume 19
pp. 539 – 549

Abstract

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Eveline de Haan,1,2 Gert R Roukema,1 Veronique AJIM van Rijckevorsel,1 Tjallingius M Kuijper,3 Louis de Jong1 On behalf of Dutch Hip Fracture RegistryCollaboration1Surgery Department, Maasstad Hospital, Rotterdam, Zuid-Holland, the Netherlands; 2Surgery Department, Franciscus Hospital, Rotterdam, Zuid-Holland, the Netherlands; 3Science Board, Maasstad Hospital, Rotterdam, Zuid-Holland, the NetherlandsCorrespondence: Eveline de Haan, Email [email protected]: The primary objective of this study was to identify new risk factors and to confirm previously reported risk factors associated with 30-day mortality after hip fracture surgery.Patients and methods: A prospective hip fracture database was used to obtain data. In total, 3523 patients who underwent hip fracture surgery between 2011 and 2021 were included. Univariable and multivariable logistic regression was used to screen and identify candidate risk factors. Twenty-seven baseline factors and 16 peri-operative factors were included in the univariable analysis and 28 of those factors were included in multivariable analysis.Results: 8.6% of the patients who underwent hip fracture surgery died within 30 days after surgery. Prognostic factors associated with 30-day mortality after hip fracture surgery were as follows: age 90– 100 years (OR = 4.7, 95% CI: 1.07– 19.98, p = 0.041) and above 100 years (OR = 11.3, 95% CI: 1.28– 100.26, p = 0.029), male gender (OR = 2.6, 95% CI: 1.97– 3.33, p < 0.001), American Society of Anesthesiologists (ASA) 3 and ASA 4 (OR = 2.1, 95% CI: 1.44– 3.14, p < 0.001), medical history of dementia (OR = 1.7, 95% CI: 1.25– 2.36, p = 0.001), decreased albumin level (OR = 0.94, 95% CI: 0.92– 0.97, p < 0.001), decreased glomerular filtration rate (GFR) (OR = 0.98, 95% CI: 0.98– 0.99, p < 0.001), residential status of nursing home (OR = 2.1, 95% CI: 1.44– 2.87, p < 0.001), higher Katz Index of Independence in Activities of Daily Living (KATZ-ADL) score (OR = 1.1, 95% CI: 1.01– 1.16, p=0.018) and postoperative pneumonia (OR = 2.4, 95% CI: 1.72– 3.38, p < 0.001).Conclusion: A high mortality rate in patients after acute hip fracture surgery is known. Factors that are associated with an increased mortality are age above 90 years, male gender, ASA 3 and ASA 4, medical history of dementia, decreased albumin, decreased GFR, residential status of nursing home, higher KATZ-ADL score and postoperative pneumonia.Keywords: hip fracture, mortality, independent risk factors, clinical outcomes

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