Peritoneal malignant mesothelioma with epithelioid type, demonstrating high serum and ascitic KL-6 levels: immunohistochemical analyses

Saifun Nahar; Manabu Nakamoto; Akira Hokama; Chiharu Kobashigawa; Masatoshi Kaida; Tetsu Kinjo; Tetsuo Hirata; Nagisa Kinjo; Masanao Saio; Naoki Yoshimi; Yuji Ohtsuki; Jiro Fujita

doi:10.4081/rt.2015.5947

Rare Tumors (Sep 2015)

Peritoneal malignant mesothelioma with epithelioid type, demonstrating high serum and ascitic KL-6 levels: immunohistochemical analyses

Saifun Nahar,
Manabu Nakamoto,
Akira Hokama,
Chiharu Kobashigawa,
Masatoshi Kaida,
Tetsu Kinjo,
Tetsuo Hirata,
Nagisa Kinjo,
Masanao Saio,
Naoki Yoshimi,
Yuji Ohtsuki,
Jiro Fujita

Affiliations

Saifun Nahar: Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihnara
Manabu Nakamoto: Department of Endoscopy, University of the Ryukyus, Nishihnara
Akira Hokama: Department of Endoscopy, University of the Ryukyus, Nishihnara
Chiharu Kobashigawa: Department of Endoscopy, University of the Ryukyus, NishihnaraUniversity of the Ryukyus
Masatoshi Kaida: Department of Endoscopy, University of the Ryukyus, Nishihnara
Tetsu Kinjo: Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihnara
Tetsuo Hirata: Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihnara
Nagisa Kinjo: Department of Endoscopy, University of the Ryukyus, Nishihnara
Masanao Saio: Department of Pathology and Oncology, University of the Ryukyus, Nishihnara
Naoki Yoshimi: Department of Pathology and Oncology, University of the Ryukyus, Nishihnara
Yuji Ohtsuki: Division of Pathology, Matsuyama-shimin Hospital
Jiro Fujita: Department of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus, Nishihnara

DOI: https://doi.org/10.4081/rt.2015.5947
Journal volume & issue: Vol. 7, no. 3

Abstract

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We report a case of KL-6 producing peritoneal malignant mesothelioma. A 56-year-old woman was referred to our hospital on November 2005 with severe abdominal distention. Peritoneal malignant mesothelioma with epithelioid type was diagnosed by clinical symptoms, laboratory investigations, imaging studies, and immunohistochemical examination of known tumor markers. In addition, high serum and ascitic KL-6 levels were observed and the immunostaining of the tumor for KL-6 was evident. We thus consider KL-6 to be a potential novel marker for peritoneal malignant mesothelioma with epithelioid type.

Published in Rare Tumors

ISSN: 2036-3605 (Print); 2036-3613 (Online)
Publisher: SAGE Publishing
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: http://journals.sagepub.com/home/rtu

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