Beilstein Journal of Organic Chemistry (Apr 2020)
Efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates
Abstract
Herein, we present an efficient synthesis of dipeptide analogues of α-fluorinated β-aminophosphonates. Each step of the synthesis was optimized to provide excellent yields. Moreover, the absolute configuration of the obtained compounds was determined by X-ray analysis, which proved the stereochemistry that was proposed based on NMR studies.
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