Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy

Abstract

Stem cell transplantation has huge potential but can suffer from effects caused by disease state microenvironment. Here, the authors report on the development of a nanozyme reinforced hydrogel for reactive oxygen species scavenging and the generation of dissolved oxygen, demonstrating improved osteointegration using the hydrogel.