Symposium 3: Impaired fasting glycemia: is it time to modify the cut-off value adopted by Argentina?

Abstract

At the end of the last century, in 1997, an International Committee of Experts convened by the American Diabetes Association (ADA) reassessed the classification and diagnostic criteria for diabetes mellitus (DM)1 defining, for the first time, the category called Impaired Fasting Glycemia (IFG), establishing its range between ≥110 mg/dL and <126 mg/dL, with the intention of establishing it as analogous to Impaired Glucose Tolerance (IGT), previously defined in a range of ≥140 and <200 mg/dL at 120 minutes of the Oral Glucose Tolerance Test (OGTT). Very shortly after, the World Health Organization (WHO) adopted much of what was resolved by the ADA, but advising that those with IFG undergo an OGTT to rule out or confirm the presence of IGT or DM2. Later, at the beginning of this century, the ADA again brought together its experts to reevaluate what was previously defined and they decided, based on the new evidence regarding progression to DM and the appearance of macroangiopathic complications, to redefine the lower limit of IFG adopting 100 mg/dL3.

Keywords

• prediabetes
• hba1c
• hemoglobina glicosilada
• glucemia en ayunas alterada
• glucemia normal