Journal for ImmunoTherapy of Cancer (Nov 2023)

1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in the TRAC locus outperforms lentiviral-based engineering of T cells

  • Philip D Greenberg,
  • Christopher A Klebanoff,
  • Kim Nguyen,
  • Gary Shapiro,
  • Joshua Francis,
  • Cheryl Black,
  • Anthony Thomas,
  • Meghan D Storlie,
  • Allison P Drain,
  • Nicholas Rouillard,
  • Nathaniel Swanson,
  • Santosh Narayan,
  • Tyler Warner,
  • Nicole Danek,
  • Ken Gareau,
  • James Parsons,
  • Jinsheng Liang,
  • Luhua Shen,
  • Tanya Tetrault,
  • Vince Nguyen,
  • Iqraa Priyata,
  • Sarah Vidyasagar,
  • Xingyue He,
  • Patrick J Browne,
  • Rebecca C Lamothe,
  • Gregory J Cost,
  • Thomas M Schmitt,
  • Smita S Chandran,
  • Ankit Gupta,
  • Damien Hallet,
  • Loic Vincent

DOI
https://doi.org/10.1136/jitc-2023-SITC2023.1223
Journal volume & issue
Vol. 11, no. Suppl 1

Abstract

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