Journal for ImmunoTherapy of Cancer (Nov 2023)
1223 Non-viral targeted knock-in of a KRAS G12D specific TCR, CD8αβ, and chimeric cytokine receptor in the TRAC locus outperforms lentiviral-based engineering of T cells
- Philip D Greenberg,
- Christopher A Klebanoff,
- Kim Nguyen,
- Gary Shapiro,
- Joshua Francis,
- Cheryl Black,
- Anthony Thomas,
- Meghan D Storlie,
- Allison P Drain,
- Nicholas Rouillard,
- Nathaniel Swanson,
- Santosh Narayan,
- Tyler Warner,
- Nicole Danek,
- Ken Gareau,
- James Parsons,
- Jinsheng Liang,
- Luhua Shen,
- Tanya Tetrault,
- Vince Nguyen,
- Iqraa Priyata,
- Sarah Vidyasagar,
- Xingyue He,
- Patrick J Browne,
- Rebecca C Lamothe,
- Gregory J Cost,
- Thomas M Schmitt,
- Smita S Chandran,
- Ankit Gupta,
- Damien Hallet,
- Loic Vincent
Affiliations
- Philip D Greenberg
- 5University of Washington School of Medicine, Seattle, WA, USA
- Christopher A Klebanoff
- Memorial Sloan Kettering Cancer Center, New York, NY, USA
- Kim Nguyen
- 3Massachusetts Institute of Technology, Cambridge, MA, USA
- Gary Shapiro
- 1Affini-T Therapeutics, Watertown, MA, USA
- Joshua Francis
- 1Affini-T Therapeutics, Watertown, MA, USA
- Cheryl Black
- 1Affini-T Therapeutics, Watertown, MA, USA
- Anthony Thomas
- 1Affini-T Therapeutics, Watertown, MA, USA
- Meghan D Storlie
- 3Metagenomi Inc, Emeryville, CA, USA
- Allison P Drain
- 1Affini-T Therapeutics, Watertown, MA, USA
- Nicholas Rouillard
- 1Affini-T Therapeutics, Watertown, MA, USA
- Nathaniel Swanson
- 1Affini-T Therapeutics, Watertown, MA, USA
- Santosh Narayan
- 1Affini-T Therapeutics, Watertown, MA, USA
- Tyler Warner
- 1Affini-T Therapeutics, Watertown, MA, USA
- Nicole Danek
- 1Affini-T Therapeutics, Watertown, MA, USA
- Ken Gareau
- 1Affini-T Therapeutics, Watertown, MA, USA
- James Parsons
- 1Affini-T Therapeutics, Watertown, MA, USA
- Jinsheng Liang
- 1Affini-T Therapeutics, Watertown, MA, USA
- Luhua Shen
- 1Affini-T Therapeutics, Watertown, MA, USA
- Tanya Tetrault
- 1Affini-T Therapeutics, Watertown, MA, USA
- Vince Nguyen
- 1Affini-T Therapeutics, Watertown, MA, USA
- Iqraa Priyata
- 1Affini-T Therapeutics, Watertown, MA, USA
- Sarah Vidyasagar
- 1Affini-T Therapeutics, Watertown, MA, USA
- Xingyue He
- 1Affini-T Therapeutics, Watertown, MA, USA
- Patrick J Browne
- 2Metagenomi Inc, Los Angeles, CA, USA
- Rebecca C Lamothe
- 3Metagenomi Inc, Emeryville, CA, USA
- Gregory J Cost
- 3Metagenomi Inc, Emeryville, CA, USA
- Thomas M Schmitt
- 4Fred Hutchinson Cancer Research Center, Seattle, WA, USA
- Smita S Chandran
- 6Memorial Sloan Kettering Cancer Center, New York, NY, USA
- Ankit Gupta
- 1Affini-T Therapeutics, Watertown, MA, USA
- Damien Hallet
- 1Affini-T Therapeutics, Watertown, MA, USA
- Loic Vincent
- 1Affini-T Therapeutics, Watertown, MA, USA
- DOI
- https://doi.org/10.1136/jitc-2023-SITC2023.1223
- Journal volume & issue
-
Vol. 11,
no. Suppl 1
Abstract
No abstracts available.
