Synthesis of C-Arylnucleoside Analogues

Abstract

Modified nucleoside analogues are of great biological importance as antiviral and antitumoral agents. There is special interest in the preparation of C-aryl nucleosides with an aromatic ring in different positions of the glycone for their biological activity. Different chemical synthesis strategies for these targets are described in this review.

Keywords

• C-arylnucleoside
• nucleoside
• carbohydrate
• total synthesis
• asymmetric catalysis