Implantomics: A Paradigm Shift in Implantology

Abstract

Implantomics is the science of the implantome. The implantome is a blend of the two terms implant and proteome. The proteome is defined as the protein complement of the genome. The term proteome also implies the mass screening of proteins for the determination of all proteins - and indirectly of all genes - involved in a certain tissue or organ response. In this sense the term proteome is employed here in a new way to specify the totality of proteins associated with a foreign body inserted into the human body. It will be addressed, why the determination of the implanttome is important and which role the implantome may play in the bone-implant interface.

Keywords

• implant proteome
• bone-implant interface
• biocompatibility
• osseointegration
• peri-implant bone healing