Iranian Journal of Otorhinolaryngology (May 2017)

Chondroradionecrosis of the Larynx in a Patient with Laryngeal: A Case Report

  • Aslan Ahmadi,
  • Mohammad Mahdi Salem,
  • Mahdi Safdarian,
  • Shahriar Ilkhani,
  • Roghaiieh Hamidian,
  • Mostafa Cheraghipour,
  • Ali Daneshvar,
  • Farzad Izadi

DOI
https://doi.org/10.22038/ijorl.2017.8649
Journal volume & issue
Vol. 29, no. 3
pp. 175 – 180

Abstract

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Introduction: Actinomycosis of the larynx has been rarely reported in the literature and usually occurs in patients with a history of laryngeal carcinoma and radiation therapy. However, its co-existence with chondroradionecrosis due to radiotherapy is even rarer. The most common site of infection is the cervicofacial region, especially in the submandibular area. Case Report: Here we report a 63-year-old male with a history of chemoradiotherapy because of laryngeal cancer 1 year earlier who presented with laryngeal actinomycosis. After prolonged penicillin-based treatment, the patient underwent thyroid cartilage defect reconstructive surgery because of a laryngocutaneous fistula due to chondroradionecrosis. The diagnosis, work-up, and management of the case are discussed, as well as a review of the literature. Conclusion: Although actinomycotic infection of the larynx is rare, it should be considered in the differential diagnosis of laryngeal complaints, especially in immunocompromised patients.

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