Non-Coding RNA (Apr 2016)

Are We Eating Our Way to Prostate Cancer—A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150

  • Venkatesh Vaidyanathan,
  • Vetrivhel Krishnamoorthy,
  • Nishi Karunasinghe,
  • Anower Jabed,
  • Radha Pallati,
  • Chi Hsiu-Juei Kao,
  • Alice Wang,
  • Gareth Marlow,
  • Lynnette R. Ferguson

DOI
https://doi.org/10.3390/ncrna2020002
Journal volume & issue
Vol. 2, no. 2
p. 2

Abstract

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MicroRNAs (miRNAs) are well established epigenetic modifiers. There is a lot of work being done to identify the evolutionary transfer of miRNAs both at intra- and interspecific levels. In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnostic biomarker for prostate cancer using theories of evolution, bio-accumulation, and interspecific transfer of miRNAs.

Keywords