Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma

Ji-Hea Kim; Ji-Hyeon Hong; Ka-Won Kang; Byung-Hyun Lee; Young Park; Byung-Soo Kim

Stem Cell Research (Dec 2022)

Generation of the human pluripotent stem cell lines KUMi005-A from a patients with multiple myeloma

Ji-Hea Kim,
Ji-Hyeon Hong,
Ka-Won Kang,
Byung-Hyun Lee,
Young Park,
Byung-Soo Kim

Affiliations

Ji-Hea Kim: Institute of Stem Cell Research, Korea University College of Medicine, Seoul, South Korea; Department of Biomedical and Science, Graduate School of Medicine, Korea University, Seoul, South Korea
Ji-Hyeon Hong: Institute of Stem Cell Research, Korea University College of Medicine, Seoul, South Korea
Ka-Won Kang: Department of Internal Medicine, Korea University Medical School Hospital, Seoul, South Korea
Byung-Hyun Lee: Department of Internal Medicine, Korea University Medical School Hospital, Seoul, South Korea
Young Park: Department of Internal Medicine, Korea University Medical School Hospital, Seoul, South Korea
Byung-Soo Kim: Institute of Stem Cell Research, Korea University College of Medicine, Seoul, South Korea; Department of Biomedical and Science, Graduate School of Medicine, Korea University, Seoul, South Korea; Department of Internal Medicine, Korea University Medical School Hospital, Seoul, South Korea; Corresponding author.

Journal volume & issue: Vol. 65
p. 102939

Abstract

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Multiple myeloma (MM) progresses with abnormal monoclonal proliferation and accumulation of malignant plasma cells in the bone marrow. We established human induced pluripotent stem cells (iPSCs), KUMi005-A, from bone marrow samples of a patient with MM. This reprogrammed cell line has similar characteristics to human embryonic stem cells, such as proliferation properties and pluripotency. KUMi005-A iPSCs may be applicable in MM disease modeling and cell-based therapies.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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