SPECIAL FEATURES OF CARDIOVASCULAR SYSTEM STATES IN PATIENTS WITH CORONARY ARTERY DISEASE AND SUBCLINICAL THYROID DYSFUNCTION

Abstract

The influence of clinically apparent thyroid dysfunction on cardiovascular system is indisputable. However, until now there is no clarity weather hypothyroidism, particularly its subclinical form, influences the coronary heart disease (CRT)) course. 102 patients with CRT) who have no thyroid dysfunction and who have nontoxic colloid nodular goiter were included in the present study. Subclinical decrease of thyroid function was revealed in 24 patients (23 % of events). Used methods included 24-hour electrocardiography and blood pressure (BP) monitoring, determination of plasma thyroid hormones and thyrotropin, ultrasound imaging of thyroid gland. The results showed that all groups of patients with CRD independently of thyroid function have a silent myocardial ischemia prevailed over painful myocardial ischemia as in frequency and as in duration. Diastolic BP and heart rate meanings were in a reverse dependence on thyroid hormone plasma levels that was more evidential in patients with subclinical thyroid dysfunction.

Keywords

• coronary heart disease
• thyroid dysfunction
• subclinical hypothyroidism
• nontoxic goiter