Radiology Case Reports (Dec 2021)

CT and MR imaging of laryngeal metastasis from renal cell carcinoma: A case report

  • Akira Baba, MD, PhD,
  • Satoshi Matsushima, MD, PhD,
  • Ryo Kurokawa, MD, PhD,
  • Reina Kayama, MD, PhD,
  • Mariko Kurokawa, MD,
  • Yoshiaki Ota, MD,
  • Hideomi Yamauchi, MD, PhD,
  • Hirokazu Ashida, MD, PhD,
  • Matsusato Tsuyumu, MD,
  • Norihiko Uchio, MD,
  • Hiroya Ojiri, MD, PhD

Journal volume & issue
Vol. 16, no. 12
pp. 3927 – 3930

Abstract

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Laryngeal metastasis is an extremely rare condition. To the best of our knowledge, there has been no previous report on a laryngeal metastasis from renal cell carcinoma, which describes on details of the CT and MR imaging findings. A male patient in his 80s. Laryngoscopy revealed reddish-colored masses in the right false vocal cord and in the subglottic larynx. CT and MR imaging of this case showed multiple hypervascularized lesions with a wash-out effect in the supra and subglottis of the larynx and in the right intervertebral foramen of the cervical spine. Angiography revealed a hypervascular tumor consistent with the subglottic lesion. The histopathology and immunohistochemistry findings were compatible with laryngeal metastasis from renal clear cell carcinoma. A history of postoperative renal clear cell carcinoma about 7 years ago was later confirmed, which was not stated at the time of the initial imaging evaluation. It is a possible differential diagnosis in cases of multiple hypervascular masses in the head and neck region with a history of renal carcinoma. In particular, if the contrast-enhancement pattern of the lesion on the dynamic CT is similar to that of renal cell carcinoma. It is also important to reconfirm the patient's medical history, including postoperative status.

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