BMC Ophthalmology (Nov 2022)

Diabetic retinopathy and corneal endothelial parameters: an analytical cross-sectional study

  • Seyed-Ali-Akbar Mortazavi,
  • Mohammadreza Akhlaghi,
  • Alireza Dehghani,
  • Mohsen Pourazizi,
  • Mohammad Malekahmadi,
  • Mohammadreza Fazel,
  • Mehdi Tavakoli,
  • Pegah Noorshargh

DOI
https://doi.org/10.1186/s12886-022-02667-6
Journal volume & issue
Vol. 22, no. 1
pp. 1 – 7

Abstract

Read online

Abstract Background To investigate the possible association of different pattern of diabetic retinopathy (DR) on corneal endothelium cells in type 2 diabetes mellitus patients. Methods In this descriptive-analytical cross-sectional study, corneal endothelium parameters including endothelial cell density (ECD), average cell size (AVG), coefficient of variation in cell size (CV), and hexagonality (Hex) were evaluated by non-contact specular microscopy. Results One hundred and thirty-four eyes of 134 diabetic patients including 77 females (57.5%) with a mean age of 61.03 ± 8.08 years were enrolled. The overall corneal parameters in diabetic patients with and without retinopathy were not significantly different (P > 0.05). There is a significant relationship between CV and the duration of the disease with age variable control (B = 0.369, p-value < 0.001). Conclusions Corneal endothelial parameters were not associated with DM in patients without and with DR. There is a significant relationship between CV and the duration of the disease with age variable control.

Keywords