Nature Communications (Apr 2021)
Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections
- Aissata Barry,
- John Bradley,
- Will Stone,
- Moussa W. Guelbeogo,
- Kjerstin Lanke,
- Alphonse Ouedraogo,
- Issiaka Soulama,
- Issa Nébié,
- Samuel S. Serme,
- Lynn Grignard,
- Catriona Patterson,
- Lindsey Wu,
- Jessica J. Briggs,
- Owen Janson,
- Shehu S. Awandu,
- Mireille Ouedraogo,
- Casimire W. Tarama,
- Désiré Kargougou,
- Soumanaba Zongo,
- Sodiomon B. Sirima,
- Matthias Marti,
- Chris Drakeley,
- Alfred B. Tiono,
- Teun Bousema
Affiliations
- Aissata Barry
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- John Bradley
- MRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine
- Will Stone
- Department of Immunology and Infection, London School of Hygiene and Tropical Medicine
- Moussa W. Guelbeogo
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Kjerstin Lanke
- Radboud Institute for Health Sciences and Radboud Center for Infectious Diseases, Radboud University Medical Centre
- Alphonse Ouedraogo
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Issiaka Soulama
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Issa Nébié
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Samuel S. Serme
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Lynn Grignard
- Department of Immunology and Infection, London School of Hygiene and Tropical Medicine
- Catriona Patterson
- Department of Immunology and Infection, London School of Hygiene and Tropical Medicine
- Lindsey Wu
- Department of Immunology and Infection, London School of Hygiene and Tropical Medicine
- Jessica J. Briggs
- Department of Medicine, University of California San Francisco
- Owen Janson
- Department of Medicine, University of California San Francisco
- Shehu S. Awandu
- Radboud Institute for Health Sciences and Radboud Center for Infectious Diseases, Radboud University Medical Centre
- Mireille Ouedraogo
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Casimire W. Tarama
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Désiré Kargougou
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Soumanaba Zongo
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Sodiomon B. Sirima
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Matthias Marti
- Wellcome Centre for Integrative Parasitology, University of Glasgow
- Chris Drakeley
- MRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine
- Alfred B. Tiono
- Centre National de Recherche et de Formation sur le Paludisme (CNRFP)
- Teun Bousema
- Radboud Institute for Health Sciences and Radboud Center for Infectious Diseases, Radboud University Medical Centre
- DOI
- https://doi.org/10.1038/s41467-021-22573-7
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 12
Abstract
In this longitudinal study of an incident (new infections) and chronic (asymptomatic infections) cohort of Plasmodium falciparum infection in children in Burkina Faso, the authors show higher gametocyte production and mosquito infectivity in chronic infections.
