Journal of Clinical Medicine (Jan 2022)
Association between CHADS<sub>2</sub>, CHA<sub>2</sub>DS<sub>2</sub>-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients
- Hyung Jun Kim,
- Moo-Seok Park,
- Joonsang Yoo,
- Young Dae Kim,
- Hyungjong Park,
- Byung Moon Kim,
- Oh Young Bang,
- Hyeon Chang Kim,
- Euna Han,
- Dong Joon Kim,
- JoonNyung Heo,
- Jin Kyo Choi,
- Kyung-Yul Lee,
- Hye Sun Lee,
- Dong Hoon Shin,
- Hye-Yeon Choi,
- Sung-Il Sohn,
- Jeong-Ho Hong,
- Jong Yun Lee,
- Jang-Hyun Baek,
- Gyu Sik Kim,
- Woo-Keun Seo,
- Jong-Won Chung,
- Seo Hyun Kim,
- Sang Won Han,
- Joong Hyun Park,
- Jinkwon Kim,
- Yo Han Jung,
- Han-Jin Cho,
- Seong Hwan Ahn,
- Sung Ik Lee,
- Kwon-Duk Seo,
- Yoonkyung Chang,
- Tae-Jin Song,
- Hyo Suk Nam,
- on behalf of the SECRET Study Investigators
Affiliations
- Hyung Jun Kim
- Department of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, Korea
- Moo-Seok Park
- Department of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, Korea
- Joonsang Yoo
- Department of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin 16995, Korea
- Young Dae Kim
- Department of Neurology, Yonsei University College of Medicine, Seoul 03722, Korea
- Hyungjong Park
- Department of Neurology, Keimyung University School of Medicine, Daegu 42601, Korea
- Byung Moon Kim
- Department of Radiology, Yonsei University College of Medicine, Seoul 03722, Korea
- Oh Young Bang
- Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea
- Hyeon Chang Kim
- Department of Preventive Medicine, Yonsei University College of Medicine, Seoul 03722, Korea
- Euna Han
- College of Pharmacy, Yonsei Institute for Pharmaceutical Research, Yonsei University, Incheon 21983, Korea
- Dong Joon Kim
- Department of Radiology, Yonsei University College of Medicine, Seoul 03722, Korea
- JoonNyung Heo
- Department of Neurology, Yonsei University College of Medicine, Seoul 03722, Korea
- Jin Kyo Choi
- Department of Neurology, Seoul Medical Center, Seoul 02053, Korea
- Kyung-Yul Lee
- Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea
- Hye Sun Lee
- Biostatistics Collaboration Unit, Department of Research Affairs, Yonsei University College of Medicine, Seoul 03722, Korea
- Dong Hoon Shin
- Department of Neurology, Gachon University Gil Medical Center, Incheon 21565, Korea
- Hye-Yeon Choi
- Department of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul 05278, Korea
- Sung-Il Sohn
- Department of Neurology, Keimyung University School of Medicine, Daegu 42601, Korea
- Jeong-Ho Hong
- Department of Neurology, Keimyung University School of Medicine, Daegu 42601, Korea
- Jong Yun Lee
- Department of Neurology, National Medical Center, Seoul 04564, Korea
- Jang-Hyun Baek
- Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea
- Gyu Sik Kim
- Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang 10444, Korea
- Woo-Keun Seo
- Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea
- Jong-Won Chung
- Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea
- Seo Hyun Kim
- Department of Neurology, Yonsei University Wonju College of Medicine, Wonju 26426, Korea
- Sang Won Han
- Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, Korea
- Joong Hyun Park
- Department of Neurology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul 01757, Korea
- Jinkwon Kim
- Department of Neurology, Yonsei University College of Medicine, Seoul 03722, Korea
- Yo Han Jung
- Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea
- Han-Jin Cho
- Department of Neurology, Pusan National University School of Medicine, Busan 49241, Korea
- Seong Hwan Ahn
- Department of Neurology, Chosun University School of Medicine, Gwangju 61453, Korea
- Sung Ik Lee
- Department of Neurology, Sanbon Hospital, Wonkwang University School of Medicine, Gunpo 15865, Korea
- Kwon-Duk Seo
- Department of Neurology, National Health Insurance Service Ilsan Hospital, Goyang 10444, Korea
- Yoonkyung Chang
- Department of Neurology, Mokdong Hospital, College of Medicine, Ewha Woman’s University, Seoul 07985, Korea
- Tae-Jin Song
- Department of Neurology, Seoul Hospital, College of Medicine, Ewha Woman’s University, Seoul 07804, Korea
- Hyo Suk Nam
- Department of Neurology, Yonsei University College of Medicine, Seoul 03722, Korea
- on behalf of the SECRET Study Investigators
- DOI
- https://doi.org/10.3390/jcm11010274
- Journal volume & issue
-
Vol. 11,
no. 1
p. 274
Abstract
Background: The CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p 2 score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198–2.009, p = 0.001; CHA2DS2VASc score: OR 1.269, 95% CI 1.080–1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011–1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167–1.849, p = 0.001). The CHADS2 score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS2 score; 0.618, 95% CI 0.554–0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.
Keywords