A late diagnosis of MEN 1 Syndrome in a young patient initially pre-senting with nephrolithiasis

Abstract

Multiple Endocrine Neoplasms Type 1 (MEN 1), originally called Wermer Syndrome, is a rare hereditary condition caused by mutations in the MEN1 tumor suppressor gene. It is characterized by tumors of the parathyroid glands, the anterior pituitary gland and pan-creatic islet cells. Hyperparathyroidism is the most common manifestation of this syndro-me. MEN1 can also be associated with other endocrine and non – endocrine tumors.

Keywords

• hyperparathyroidism, MEN-1 Syndrome, nephrolithiasis, neuroendocrine tumors