Revista Peruana de Medicina Experimental y Salud Pública (Nov 2021)

SARS-CoV-2 variants: epidemiology, pathophysiology and the importance of vaccines

  • Marcelo Bedoya-Sommerkamp,
  • Jesús Medina-Ranilla,
  • Víctor Chau-Rodríguez,
  • Renato Li-Soldevilla,
  • Álvaro Vera-Albújar,
  • Patricia J. García

DOI
https://doi.org/10.17843/rpmesp.2021.383.8734
Journal volume & issue
Vol. 38, no. 3
pp. 442 – 51

Abstract

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SARS-CoV-2 is a single-stranded RNA virus of the coronavirus family, which causes COVID-19 (Coronavirus Disease 2019). This virus is responsible for the current pandemic, which, since its emergence in late 2019, has caused millions of deaths and has had a global impact not only on public health but also on social and economic areas. Therefore, this article aims to review the most up-to-date information on SARS-CoV-2, beginning with the description of the pathophysiology and phylogenetics of the virus. Also, we will present the emerging SARS-CoV-2 variants, their relevance for local and global public health, their epidemiology in Peru, and finally, the role and importance of vaccines in this context.

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