Liquid-state carbon-13 hyperpolarization generated in an MRI system for fast imaging

A. B. Schmidt; S. Berner; W. Schimpf; C. Müller; T. Lickert; N. Schwaderlapp; S. Knecht; J. G. Skinner; A. Dost; P. Rovedo; J. Hennig; D. von Elverfeldt; J. -B. Hövener

doi:10.1038/ncomms14535

Nature Communications (Mar 2017)

Liquid-state carbon-13 hyperpolarization generated in an MRI system for fast imaging

A. B. Schmidt,
S. Berner,
W. Schimpf,
C. Müller,
T. Lickert,
N. Schwaderlapp,
S. Knecht,
J. G. Skinner,
A. Dost,
P. Rovedo,
J. Hennig,
D. von Elverfeldt,
J. -B. Hövener

Affiliations

A. B. Schmidt: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
S. Berner: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
W. Schimpf: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
C. Müller: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
T. Lickert: Division Hydrogen Technologies, Fraunhofer Institute for Solar Energy Systems (ISE)
N. Schwaderlapp: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
S. Knecht: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
J. G. Skinner: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
A. Dost: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
P. Rovedo: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
J. Hennig: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
D. von Elverfeldt: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg
J. -B. Hövener: Department of Radiology, Medical Physics, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg

DOI: https://doi.org/10.1038/ncomms14535
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 8

Abstract

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Hyperpolarized MRI uses molecules with a nuclear spin polarization beyond the thermodynamic equilibrium to enhance imaging contrast. Here, Schmidtet al. enable a single MRI system to both generate a hyperpolarized tracer and perform imaging, eliminating the need for an external polarizer.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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