Acta Biomedica Scientifica (May 2012)

DYNAMICS OF SURFACE EXPRESSION OF TRIGGER RECEPTOR, EXPRESSED BY MYELOID CELLS-1 (TREM-1) ON VARIOUS SUBPOPULATIONS OF MONOCYTES IN EARLY POSTOPERATIVE PERIOD OF DIRECT REVASCULARIZATION OF MYOCARDIUM

  • V. G. Matveyeva,
  • A. S. Golovkin,
  • M. N. Chernova,
  • D. L. Shukevich,
  • E. V. Grigoryev

Journal volume & issue
Vol. 0, no. 3(2)
pp. 116 – 120

Abstract

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We studied surface expression of trigger receptor, expressed by myeloid cells-1 (TREM-1) on various subpopulations of monocytes before direct revascularization of myocardium with artificial blood flow and in early postoperative period. We registered that various expression of TREM-1 on the surface corresponds to subpopulations of monocytes, and the highest level is observed on CD14hiCD16+ monocytes. By the 1st day of postoperative period elevation of surface expression of TREM-1 occurs on all subpopulations of monocytes, testifying to enlargement of their proinflammatory potential.

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