Salud Pública de México (Mar 2015)

Primary drug resistance in a region with high burden of tuberculosis. A critical problem

  • Cecilia Villa-Rosas,
  • Rafael Laniado-Laborín,
  • Lorena Oceguera-Palao

DOI
https://doi.org/10.21149/spm.v57i2.7414
Journal volume & issue
Vol. 57, no. 2
pp. 177 – 179

Abstract

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Objective. To determine rates of drug resistance in new cases of pulmonary tuberculosis in a region with a high burden of the disease. Materials and methods. New case suspects were referred for drug susceptibility testing. Results. 28.9% of new cases were resistant to at least one first line drug; 3.9% had a multidrug-resistant strain, 15.6% a monoresistant strain and 9.4% a polyresistant strain. Conclusion. Our rate of drug resistant tuberculosis in new cases is very high; this has important clinical implications, since even monoresistance can have a negative impact on the outcome of new cases treated empirically with a six month regimen.

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