Role of depression in Alzheimer’s disease

Abstract

Old age population in developing countries is rising as also chronic diseases like Alzheimer’s disease (AD) with increase in morbidity and disability. Depression is considered increasingly both as a risk factor and prodromal feature in AD. Depression and Diabetes mellitus are now both considered as risk factors in conversion of Mild Cognitive Impairment (MCI) to AD with neuro-inflammation as a possible underlying cause. Cognitive deficits occurring in old age should be evaluated thoroughly and followed up at regular intervals.

Keywords

• alzheimer’s disease
• depression
• mci
• risk
• prodrome.