PLoS ONE (Jan 2020)

Massachusetts general hospital Covid-19 registry reveals two distinct populations of hospitalized patients by race and ethnicity.

  • Ingrid V Bassett,
  • Virginia A Triant,
  • Bridget A Bunda,
  • Caitlin A Selvaggi,
  • Daniel J Shinnick,
  • Wei He,
  • Frances Lu,
  • Bianca C Porneala,
  • Tingyi Cao,
  • Steven A Lubitz,
  • James B Meigs,
  • John Hsu,
  • Andrea S Foulkes

DOI
https://doi.org/10.1371/journal.pone.0244270
Journal volume & issue
Vol. 15, no. 12
p. e0244270

Abstract

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ObjectiveTo evaluate differences by race/ethnicity in clinical characteristics and outcomes among hospitalized patients with Covid-19 at Massachusetts General Hospital (MGH).MethodsThe MGH Covid-19 Registry includes confirmed SARS-CoV-2-infected patients hospitalized at MGH and is based on manual chart reviews and data extraction from electronic health records (EHRs). We evaluated differences between White/Non-Hispanic and Hispanic patients in demographics, complications and 14-day outcomes among the N = 866 patients hospitalized with Covid-19 from March 11, 2020-May 4, 2020.ResultsOverall, 43% of patients hospitalized with Covid-19 were women, median age was 60.4 [IQR = (48.2, 75)], 11.3% were Black/non-Hispanic and 35.2% were Hispanic. Hispanic patients, representing 35.2% of patients, were younger than White/non-Hispanic patients [median age 51y; IQR = (40.6, 61.6) versus 72y; (58.0, 81.7) (pConclusionsHospitalized Hispanic patients were younger and had fewer comorbidities compared to White/non-Hispanic patients; despite comparable rates of ICU care or death, a greater proportion recovered. These results have implications for public health policy and the design and conduct of clinical trials.