Two New Triterpenoids from the Roots of Codonopsis pilosula
Tao Zheng,
Li-Zhi Cheng,
Yong-Ming Yan,
Bao-Hua Liu,
Fu-Ying Qin,
Fu-Rong Xu,
Yong-Xian Cheng
Affiliations
Tao Zheng
College of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650504, China
Li-Zhi Cheng
Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, Shenzhen University Health Sciences Center, Shenzhen 518060, China
Yong-Ming Yan
Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, Shenzhen University Health Sciences Center, Shenzhen 518060, China
Bao-Hua Liu
Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, Shenzhen University Health Sciences Center, Shenzhen 518060, China
Fu-Ying Qin
College of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650504, China
Fu-Rong Xu
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China
Yong-Xian Cheng
College of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650504, China
Pseudolarolides U and V, two new triterpenoids, and four biogenetically related compounds, pseudolarolides E, F, K, and P were isolated from the roots of Codonopsis pilosula (Campanulaceae). Their structures were determined by spectroscopic data. The regulation of Sirtuin 1 (SIRT1) activity by all the isolated compounds was evaluated.
