PLoS ONE (Jan 2021)

Length of stay following percutaneous left atrial appendage occlusion: Data from the prospective, multicenter Amplatzer Amulet Occluder Observational Study.

  • Kerstin Piayda,
  • Shazia Afzal,
  • Jens Erik Nielsen-Kudsk,
  • Boris Schmidt,
  • Patrizio Mazzone,
  • Sergio Berti,
  • Sven Fischer,
  • Juha Lund,
  • Matteo Montorfano,
  • David Hildick-Smith,
  • Ryan Gage,
  • Hong Zhao,
  • Tobias Zeus

DOI
https://doi.org/10.1371/journal.pone.0255721
Journal volume & issue
Vol. 16, no. 8
p. e0255721

Abstract

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AimsTo evaluate factors influencing the length of stay in patients undergoing percutaneous left atrial appendage occlusion (LAAO).Methods and resultsPatient characteristics, procedural data and the occurrence of serious adverse events were analyzed from the AmplatzerTM AmuletTM Occluder Observational Study. Patients were divided into three groups: same day (S, 0day, n = 60, 5.6%) early (E, 1day, n = 526, 48.9%), regular (R, 2-3days, n = 338, 31.4%) and late (L, ≥4days, n = 152, 14.1%) discharge and followed up for 60 days. Procedure and device related SAE during the in-hospital stay (S: 0.0% vs. E: 1.0% vs. R: 2.1% vs. L: 23%, pConclusionOver half of the subjects receiving an Amplatzer Amulet occluder were discharged within 1 day of the implant procedure. Serious adverse events were a major trigger for a late discharge after LAAO. Increased HAS-BLED score was associated with a prolonged in-hospital stay.