Journal of Nanobiotechnology (Oct 2022)

An overview on nanoparticle-based strategies to fight viral infections with a focus on COVID-19

  • Saman Yasamineh,
  • Hesam Ghafouri Kalajahi,
  • Pooneh Yasamineh,
  • Yalda Yazdani,
  • Omid Gholizadeh,
  • Raheleh Tabatabaie,
  • Hamed Afkhami,
  • Fatemeh Davodabadi,
  • Alireza Khanalipour farkhad,
  • Daryoush Pahlevan,
  • Akram Firouzi-Amandi,
  • Kazem Nejati-Koshki,
  • Mehdi Dadashpour

DOI
https://doi.org/10.1186/s12951-022-01625-0
Journal volume & issue
Vol. 20, no. 1
pp. 1 – 26

Abstract

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Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to COVID-19 and has become a pandemic worldwide with mortality of millions. Nanotechnology can be used to deliver antiviral medicines or other types of viral reproduction-inhibiting medications. At various steps of viral infection, nanotechnology could suggest practical solutions for usage in the fight against viral infection. Nanotechnology-based approaches can help in the fight against SARS-CoV-2 infection. Nanoparticles can play an essential role in progressing SARS-CoV-2 treatment and vaccine production in efficacy and safety. Nanocarriers have increased the speed of vaccine development and the efficiency of vaccines. As a result, the increased investigation into nanoparticles as nano-delivery systems and nanotherapeutics in viral infection, and the development of new and effective methods are essential for inhibiting SARS-CoV-2 infection. In this article, we compare the attributes of several nanoparticles and evaluate their capability to create novel vaccines and treatment methods against different types of viral diseases, especially the SARS-CoV-2 disease. Graphical Abstract

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