Study on α-glucosidase inhibitory activity of 40 kinds of vegetables, tubers, and fruits in An Giang

Abstract

A study on the α-glucosidase inhibitory activity of 40 kinds of vegetables, tubers, and fruits found in the An Giang province was conducted. The results indicated that all 40 extracted samples displayed α-glucosidase inhibitory activity at a concentration of 250 µg ml-1, 36 extracted samples showed an inhibition rate greater than 50% at 250 µg ml-1, 25 extracted samples had over 50% at 100 µg ml-1, 17 extracted samples possessed more than 50% at 50 µg ml-1, 7 extracted samples sampled showed over 50% at 25 µg ml-1, 5 extracted samples were greater than 50% at 10 µg ml-1, and 1 extracted sample was greater than 50% at 1 µg ml-1. Among the 40 samples, those taken from the seeds of Areca catechu, the fruits of Cassia grandis, the fruits of Syzygium cumini, the seeds of Glycine max, and the stems of Enydra fluctuans exhibited the strongest α-glucosidase inhibitory activity in methanol, with IC50 values of 0.15, 2.54, 4.05, 5.17 and 8.68 µg ml-1, respectively, which were stronger than the positive control acarbose with an IC50 value of 214.5 µg ml-1.

Keywords

• An Giang
• α-glucosidase
• Areca catechu
• Cassia grandis
• fruit
• Glycine max and Enydra fluctuans